OBJECTIVE: To report and identify the predictors of early and long-term complications in a large series of extraperitoneal robot-assisted radical prostatectomy using the standardized Martin criteria.
MATERIALS AND METHODS: A total of 1503 patients underwent extraperitoneal robot-assisted radical prostatectomy for the treatment of clinically localized prostate cancer from July 2003 to August 2010 at a tertiary referral center. The median follow-up was 28.9 months. Fisher's exact test was used to examine the association of multiple variables in a bivariate analysis with the incidence and types of complications. Independent predictors were also examined in a multivariate analysis using logistic regression models.
RESULTS: A total of 151 complications were recorded in 127 of 1503 patients (8.45%). Approximately one third (30.5%) were classified as major complications requiring intervention (Clavien grade III and IV). The most commonly encountered complications were lymphocele (1.46%), bladder neck contracture (1.33%), and anastomotic leak (1.20%). The operative time was a significant predictor of all complications and of major complications on multivariate analysis. Surgeon experience was also predictive of complications on multivariate analysis.
CONCLUSION: Extraperitoneal robot-assisted radical prostatectomy remains an underused alternative approach for the treatment of localized prostate cancer. Its safety profile is equivalent to that of other approaches in experienced hands.
Written by:
Ghazi A, Scosyrev E, Patel H, Messing EM, Joseph JV. Are you the author?
Department of Urology, University of Rochester Medical Center, Rochester, NY.
Reference: Urology. 2013 Feb;81(2):324-33.
doi: 10.1016/j.urology.2012.07.106
PubMed Abstract
PMID: 23374793
UroToday.com Prostate Cancer Section
