A 73-year-old man was admitted to our hospital with a chief complaint of hematemesis.
Two years before admission, adenocarcinoma of unknown origin was diagnosed. Since then, the patient had been taking TS-1 (pramoxine hydrochloride) medication, which caused gastroduodenal mucosal damage. A large abdominal tumor and elevated prostate specific antigen (PSA) level of 13,190 ng/ml, caused by this damage, were detected. Extensive abdominal metastasis of prostate cancer was diagnosed and combined androgen blockade was initiated. After 3 months, the PSA level decreased to 4.4 ng/ml and the abdominal tumor shrunk significantly. Physicians should keep in mind prostate cancer in the differential diagnosis of unexplained adenocarcinoma.
Written by:
Shirono Y, Hanyu S, Ikarashi T. Are you the author?
The Department of Urology, Kariwagun General Hospital.
Reference: Hinyokika Kiyo. 2013 Jan;59(1):51-5.
PubMed Abstract
PMID: 23412126
Article in Japanese.
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