Androgen deprivation therapy (ADT) for prostate cancer (PCa) treatment causes sexual dysfunction.
We review here the effects of estrogen on the sexual performance of androgen-deprived males. The major findings are: We discuss the general benefits of estrogen therapy to quality of life of men on ADT, the potential risks of this treatment, and possible treatment regimes for estrogen therapy in males. Unless contraindicated, we propose that PCa patients on ADT would benefit from supplemental parenteral estrogen.
Written by:
Wibowo E, Wassersug RJ. Are you the author?
Department of Anatomy & Neurobiology, Dalhousie University, Room 13-J, 5850 College Street, PO Box 15000, Halifax, NS B3H 4R2, Canada.
Reference: Crit Rev Oncol Hematol. 2013 Feb 25. pii: S1040-8428(13)00032-2.
doi: 10.1016/j.critrevonc.2013.01.006
PubMed Abstract
PMID: 23484454
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