BERKELEY, CA (UroToday.com) - Androgen deprivation, when combined with definitive radiotherapy for high-risk prostate cancer, has been demonstrated to improve multiple clinical outcomes, including overall survival. Although androgen deprivation can be relatively simple to administer with injections as infrequent as every 6 months, the side effects of therapy require close monitoring. Androgen deprivation impacts a variety of body systems, including metabolic, cardiovascular, musculoskeletal, neurocognitive, and sexual.
We performed a literature review with the goal of consolidating and simplifying the existing knowledge relevant to androgen deprivation side-effect management for the radiation oncologist. Additionally, we created a “checklist” style management guide to assist clinicians initiating patients on androgen deprivation, or seeing them in follow up.
Written by:
Mark Buyyounouski, MD, MS as part of Beyond the Abstract on UroToday.com. This initiative offers a method of publishing for the professional urology community. Authors are given an opportunity to expand on the circumstances, limitations etc... of their research by referencing the published abstract.
Director, Clinical Research
Department of Radiation Oncology
Fox Chase Cancer Center
Philadelphia, PA USA
Androgen deprivation therapy toxicity and management for men receiving radiation therapy - Abstract
