PURPOSE: To assess functional outcomes obtained after surgical management of post-radiation urinary incontinence after prostate cancer.
PATIENTS AND METHOD: A retrospective review of the data from patients treated in our centre between September 2004 and February 2012 by surgery for vesicosphincteric injuries after prostatic external beam radiation therapy was performed.
RESULTS: A total of seven men with a median age of 70years±4.1 were included. Mean follow-up was 32.3months±29 (3-86). All patients underwent a partial cystectomy and augmentation enterocystoplasty. The vesicocutaneous fistula rate was 33% occurring within a mean time of 18.5days±2.1 (17-20). The mean length of urinary catheter and hospital stay were respectively 16days±8.4 (12-35) and 18days±7.8 (13-37). Five patients underwent asynchronous insertion of artificial urinary sphincter. The success rate of partial cystectomy and augmentation enterocystoplasty with asynchronous implantation of artificial urinary sphincter to treat post-radiation urinary incontinence was 71.5%. The median time between partial cystectomy and augmentation enterocystoplasty and artificial urinary sphincter implantation was 27.6months±26.4 (7-72).
CONCLUSION: Surgical management of post-radiation urinary cystitis offers good functional outcomes albeit its morbidity is not negligible. It should be proposed only in expert surgical centres.
Written by:
Seisen T, Rouprêt M, Phé V, Bosset PO, Parra J, Drouin SJ, Simon JM, Chartier-Kastler E. Are you the author?
Service d'urologie, hôpital Pitié-Salpêtrière, Assistance publique-Hôpitaux de Paris, 47-83, boulevard de l'Hôpital, 75013 Paris, France; Faculté de médecine, université Pierre-et-Marie-Curie Paris VI, 47-83, boulevard de l'Hôpital, 75013 Paris, France.
Reference: Cancer Radiother. 2013 Jul-Aug;17(4):282-7.
doi: 10.1016/j.canrad.2013.04.003
PubMed Abstract
PMID: 23810305
Article in French.
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