A 59-year-old man presented with frequent urination.
Six months ago, his prostate-specific antigen (PSA) was 1.56 ng/mL; currently it is 3.5 ng/mL (PSA doubling time = 6 months; PSA velocity = 0.19 ng/mL/mo). Biopsy revealed aggressive prostate cancer (Gleason score 5 + 5). Staging with F-fluorocholine PET/CT (F-FCH PET/CT) demonstrated lymph node metastasis. After 6 months of hormonal therapy with goserelin, PSA decreased to 0.38 ng/mL. A F-FCH PET/CT restaging scan demonstrated a global reduction of F-FCH lesion uptake with disappearance of some mediastinal and iliac pelvic lymph node activity.
Written by:
Hodolič M, Maffione AM, Fettich J, Gubina B, Cimitan M, Rubello D. Are you the author?
Department of Nuclear Medicine, University Medical Centre Ljubljana, Ljubljana, Slovenia; Department of Nuclear Medicine, PET/CT Centre, Santa Maria della Misericordia Hospital Rovigo, Rovigo, Italy; Department of Urology, University Medical Centre Ljubljana, Ljubljana, Slovenia; Department of Nuclear Medicine, National Cancer Institute CRO IRCCS, Aviano, Italy.
Reference: Clin Nucl Med. 2013 Sep;38(9):739-40.
doi: 10.1097/RLU.0b013e31829b9d6b
PubMed Abstract
PMID: 23816948
