We report a case of dissemination of prostate cancer after holmium laser enucleation of the prostate in an 80-year-old patient.
The patient presented at hospital because of nocturia. Transrectal ultrasound-guided biopsy was carried out because of high serum prostate-specific antigen (3.55 ng/mL), but it showed no malignancies. Benign prostate hyperplasia was diagnosed, and he was started on an α1-blocker. Although the urinary symptom improved with silodosin, acute urinary retention occurred 3 years after therapy began. Holmium laser enucleation of the prostate for relief of bladder outlet obstruction enabled discharge of urine. Pathological examination of the resected tissue found adenocarcinoma with a high Gleason score, 4 + 5. Serum alkaline phosphatase increased rapidly after holmium laser enucleation, and bone scintigraphy confirmed multiple bone metastases. Prostate cancer, T1bN0M1b, was diagnosed.
Written by:
Koguchi D, Nishi M, Satoh T, Shitara T, Matsumoto K, Fujita T, Yoshida K, Iwamura M. Are you the author?
Department of Urology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Reference: Int J Urol. 2013 Aug 15. Epub ahead of print.
doi: 10.1111/iju.12248
PubMed Abstract
PMID: 23944756
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