Cholestatic jaundice as a paraneoplastic manifestation of prostate cancer - Abstract

Paraneoplastic syndrome associated with prostate cancer is extremely rare.

We report a patient who presented with cholestatic jaundice without biliary duct obstruction, hepatic involvement, or infection. After a few detailed examinations, prostate cancer was diagnosed. After treatment with bicalutamide and leuprolide, the patient's symptoms and laboratory abnormalities were reversed. Cholestatic jaundice was regarded as a paraneoplastic manifestation in this patient. The patient remains symptom-free after 14-month followup. Paraneoplastic syndrome should be considered in case of cholestatic jaundice without biliary duct obstruction, hepatic involvement, or infection.

Written by:
Kuramoto T, Senzaki H, Koike H, Yamagiwa K, Tamura S, Fujimoto T, Inagaki T.   Are you the author?
Department of Urology, Social Insurance Kinan Hospital, 46-70 Shinjou-chou, Tanabe-shi, Wakayama 646-8588, Japan.

Reference: Case Rep Urol. 2013;2013:303727.
doi: 10.1155/2013/303727


PubMed Abstract
PMID: 24191227

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