We present the first case of salvage retroperitoneal lymph node dissection based on the results of 18F-FACBC PET/CT performed for a prostate-specific antigen relapse after radical prostatectomy.
The patients underwent 11C-choline PET/CT, which turned out negative, while 18F-FACBC PET/CT visualized two lymph node metastases confirmed at pathological examination. Preliminary clinical reports showed an improvement in the detection rate of 20-40% for 18F-FACBC in comparison with 11C-choline, rendering the 18F-FACBC the potential radiotracer of the future. Salvage surgery for prostate cancer is a fascinating but controversial approach. New diagnostic tools may improve its potential by increasing the assessment and the selection of the patients.
Written by:
Schiavina R, Concetti S, Brunocilla E, Nanni C, Borghesi M, Gentile G, Cevenini M, Bianchi L, Molinaroli E, Fanti S, Martorana G. Are you the author?
Department of Urology, University of Bologna, Bologna, Italy.
Reference: Urol Int. 2013 Dec 7. Epub ahead of print.
doi: 10.1159/000354730
PubMed Abstract
PMID: 24334968
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