Diabetes mellitus and prostate cancer are 2 of the most important public health concerns, especially in the elderly population.
Although diabetes has been recognized as a potent risk factor for many types of cancers, there is a large amount of evidence that shows that it has a protective role against prostate cancer. The underlying cause of this protective role is not fully understood, however, some mechanisms have been proposed in this area. In the present study we have reviewed these mechanisms and some new mechanisms are also proposed.
Written by:
Rastmanesh R, Hejazi J, Marotta F, Hara N. Are you the author?
Department of Clinical Nutrition and Dietetics, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Department of Biochemistry and Nutrition, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran; ReGenera Res Group for Aging Intervention, Milan, Italy; Division of Urology, Department of Regenerative and Transplant Medicine, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan; Division of Molecular Oncology, Department of Signal Transduction Research, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.
Reference: Clin Genitourin Cancer. 2014 Jan 5. pii: S1558-7673(14)00002-0.
doi: 10.1016/j.clgc.2014.01.001
PubMed Abstract
PMID: 24513117
UroToday.com Prostate Cancer Section
