Prostate cancer is a heterogeneous, indolent or sometimes aggressive tumor.
Treatment options are various and without proved superiority. Radiotherapy (RT) plays a key role in the disease history. Technological evolution with Intensity Modulate Radiation Therapy (IMRT) and Image Guided Radiation Therapy (IGRT) allowed improvement, with significant results on local control and survival. Hypofractionation, Stereotactic Body RT (SBRT) and new brachytherapy approachs are still under investigation, with promising opportunities. Adjuvant vs salvage postoperative RT, hormone association, prophylactic pelvic irradiation are still under debate, but guidelines express overlapping indications. Multidisciplinary managements will be the future for care optimization, providing the best tool for holistic and informed patients' choice.
Written by:
Mantini G, Alitto AR, Fionda B, Frascino V, Mattiucci GC, Balducci M, Morganti AG, Valentini V. Are you the author?
Cattedra di Radioterapia Oncologica, Università Cattolica del Sacro Cuore, Facoltà di Medicina e Chirurgia, Policlinico "A. Gemelli", Roma - Italy.
Reference: Urologia. 2013 Sep 30;80(3):188-201.
doi: 10.5301/RU.2013.11499
PubMed Abstract
PMID: 24526595
Article in Italian.
UroToday.com Prostate Cancer Section
