OBJECTIVE: To compare peri-operative outcomes of open radical prostatectomy (ORP) to laparoscopic radical prostatectomy (LRP) in a single French institution.
METHODS: Between 1998 and 2003, 72 patients underwent ORP followed by 279 LRP between 2003 and 2010 for a clinically localized prostate cancer. Demographic, peri-operative and pathological data in the ORP and LRP groups were analyzed and compared.
RESULTS: In the ORP group, compared to the LRP group, the following significant differences were found: patients were older (63.1 years versus 65.6), initial PSA was higher (10.2ng/mL versus 6.7) and the proportion of T1c was higher (62.8 % versus 80.6 %). Operative blood loss (1500mL versus 500) and length of hospitalization (9.0 days versus 6.3) were higher in the ORP group (P< 0.001). Operative time was longer in the LRP group (250min versus 160; P< 0 .001). There was no significant difference regarding length of catheterization (average of 8.5 days). Anastomotic strictures were more frequent following ORP (P< 0.001). Positive margins proportion in the ORP group (7.1 %) was lower than that observed in the LRP group (28.7 %) (P=0.001). Patients in the ORP group achieved early continence more frequently (P< 0.01) but at 12 months postoperatively there was no significant difference.
CONCLUSION: Patients in the LRP group had lower operative blood losses and a shorter length of hospitalization. However, in the ORP group, operative time was shorter and positive margins rate was lower.
Written by:
Verdier E, Doré B, Fromont G, Pirès C, Lecoq B, Dezael JC, Irani J. Are you the author?
Service d'urologie, CHU de Poitiers, 2, rue de la Milétrie, 86000 Poitiers, France; Service d'anatomo-cyto-pathologie, CHU de Poitiers, rue de la Milétrie, 86000 Poitiers, France; Service d'urologie, centre hospitalier Camille-Guérin, rue Docteur-Luc-Montagnier, 86100 Chatellerault, France; Service d'urologie, clinique de l'Alliance, boulevard Alfred-Nobel, BP 30729, 37542 Saint-Cyr-Sur-Loire cedex, France.
Reference: Prog Urol. 2014 Mar;24(3):173-9.
doi: 10.1016/j.purol.2013.08.313
PubMed Abstract
PMID: 24560206
Article in French.
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