Incidental diagnosis of diffuse large B-cell lymphoma by 11C-choline PET/CT in a patient with biochemical recurrence of prostate cancer - Abstract

The main indication for ¹¹C-choline PET/CT in prostate cancer patients is the early localization of biochemical recurrence after radical treatment.

However, any ¹¹C-choline uptake should be assessed in terms of physiological distribution and patterns of tumor spread. Therefore, tracer-avid lesions in unexpected sites should be carefully addressed because the diagnosis of other malignancies has important therapeutic implications. We present a patient with biochemical recurrence of prostate cancer treated with radiotherapy. ¹¹C-choline PET/CT showed local recurrence and inguinal lymph node uptake. Because of its location beyond typically prostatic lymphatic spread, resection was performed. Histology confirmed a diffuse large B-cell lymphoma.

Written by:
Garzon JG, Bassa P, Moragas M, Soler M, Riera E.   Are you the author?
CETIR Unidad PET/TC, Barcelona, Spain.

Reference: Clin Nucl Med. 2014 Aug;39(8):742-3.
doi: 10.1097/RLU.0000000000000495

PubMed Abstract
PMID: 24978327

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