BACKGROUND: To present our experiences in initial clinical evaluation of a novel mechatronic system for in-bore guidance of needles to the prostate for MRI-guided prostate interventions in 10 patients.
We report accuracy of this device in the context of focal laser ablation therapy for localized prostate cancer.
METHODS: An MRI-compatible needle guidance device was developed for transperineal prostate interventions. Ten patients underwent MRI-guided focal laser ablation therapy with device-mediated laser fiber delivery. We recorded needle guidance error and needle delivery time.
RESULTS: A total of 37 needle insertions were evaluated. Median needle guidance error was 3.5 mm (interquartile range, 2.1-5.4 mm), and median needle delivery time was 9 min (interquartile range, 6.5-12 min).
CONCLUSION: This system provides a reliable method of accurately aligning needle guides for in-bore transperineal needle delivery to the prostate.
Written by:
Cepek J, Lindner U, Ghai S, Louis AS, Davidson SR, Gertner M, Hlasny E, Sussman MS, Fenster A, Trachtenberg J. Are you the author?
Department of Surgical Oncology, Division of Urology, University Health Network, Toronto, Canada; Robarts Research Institute, The University of Western Ontario, London, Canada.
Reference: J Magn Reson Imaging. 2014 Sep 4. Epub ahead of print.
doi: 10.1002/jmri.24742
PubMed Abstract
PMID: 25195664