Active surveillance (AS) is an important management option for men with low-risk, clinically localized prostate cancer.
The clinical parameters for patient selection and definition of progression for AS protocols are evolving as data from several large cohorts matures. Vital to this process is the critical role pathologic parameters play in identifying appropriate candidates for AS. These findings need to be reproducible and consistently reported by surgical pathologists. This report highlights the importance of accurate pathology reporting as a critical component of these protocols.
Written by:
Montironi R, Hammond EH, Lin DW, Gore JL, Srigley JR, Samaratunga H, Egevad L, Rubin MA, Nacey J, Klotz L, Sandler H, Zietman AL, Holden S, Humphrey PA, Evans AJ, Delahunt B, McKenney JK, Berney D, Wheeler TM, Chinnaiyan A, True L, Knudsen B, Epstein JI, Amin MB. Are you the author?
Section of Pathological Anatomy, School of Medicine, United Hospitals, Polytechnic University of the Marche Region, Via Conca 71, Torrette, 60126, Ancona, Italy.
Reference: Virchows Arch. 2014 Oct 16. Epub ahead of print.
doi: 10.1007/s00428-014-1668-5
PubMed Abstract
PMID: 25316188