Despite the high incidence of prostate carcinoma, metastases of the uvea are very rare and the iris localization is even more.
Only a few cases worldwide have been described so far. We report here the case of a 66-year-old man diagnosed with a metastatic prostate carcinoma. Nine months later, he developed brain and skin metastases. A couple of weeks later, the metastatic lesion appeared on his left iris. He has received whole brain radiation therapy including the iris lesion in the radiation fields. Through this case report and a literature review, we discuss the incidence, the different clinical presentations and the impact on the survival prognosis of this uncommon metastatic site.
Written by:
Martin V, Cuenca X, Lopez S, Albertini AF, Lang P, Simon JM, Hémery CG, Feuvret L, Mazeron JJ. Are you the author?
Radiation Oncology, groupe hospitalier Pitié-Salpêtrière, 47-83, boulevard de l'Hôpital, 75651 Paris cedex 13, France; Pathology Department, groupe hospitalier Pitié-Salpêtrière, 47-83, boulevard de l'Hôpital, 75651 Paris cedex 13, France.
Reference: Cancer Radiother. 2015 Apr 6. pii: S1278-3218(15)00033-5.
doi: 10.1016/j.canrad.2014.12.008
PubMed Abstract
PMID: 25858707