We aimed compare oncological outcomes in the two rare subtypes, unclassified renal cell cancer (unRCC) and translocation RCC (tRCC), vs clear cell RCC (ccRCC).
Between 2004 and 2019, from Turkish Urooncology Society Database, we identified 2324 patients for histological subtypes including 80 unRCC (3. 4%), 19 tRCC (0.8%) and 2225 ccRCC (95.8%).
The overall (15.8%) and cancer-specific mortalities (11.1%) were found to be higher in tRCC group and the recurrence free mortality (13.8%) was found to be higher in unRCC group. Larger pathological tumor size (p=0.012) and advanced pathological T stage (p=0.042) were independent predictive factors on overall mortality in patients with unRCC tumors.
The oncological outcomes of the unRCC and tRCC are worse than ccRCC and pathological tumor size and pathological stage are predictive factors for mortality in the unRCC.
Urology journal. 2022 Jul 17 [Epub ahead of print]
Fatih Gokalp, Serdar Celik, Tevfik Sinan Sozen, Abdurrahim Haluk Ozen, Guven Aslan, Volkan Izol, Sumer Baltaci, Talha Muezzinoglu, Bulent Akdogan, Evren Suer, Ilker Tinay
Department of Urology, Hatay Mustafa Kemal University, School of Medicine, Hatay. ., Department of Urology, Bozyaka Training and Research Hospital, Izmir. ., Department of Urology, Gazi University, School of Medicine, Ankara. ., Department of Urology, Hacettepe University, School of Medicine, Ankara. ., Department of Urology, Dokuz Eylul University, School of Medicine, Izmir. ., Department of Urology, Cukurova University, School of Medicine, Adana. ., Department of Urology, Ankara University, School of Medicine, Ankara. ., Department of Urology, Manisa Celal Bayar University, School of Medicine, Manisa. ., Department of Urology, Hacettepe University, School of Medicine, Ankara. ., Department of Urology, Ankara University, School of Medicine, Ankara. ., Department of Urology, Marmara University School of Medicine, Istanbul. .