Over the past decade, only minor changes have been introduced in the TNM staging system for renal cancer. Conversely, many milestones and modifications in management of the disease have been achieved, especially for patients with locally advanced and metastatic cancers. The European Association of Urology guidelines panel proposes a new TNM classification scheme for staging of renal cell carcinoma to reflect these breakthrough clinical improvements.
European urology. 2022 Oct 14 [Epub ahead of print]
Umberto Capitanio, Jens Bedke, Laurence Albiges, Alessandro Volpe, Rachel H Giles, Milan Hora, Lorenzo Marconi, Tobias Klatte, Yasmin Abu-Ghanem, Saeed Dabestani, Sergio Fernández Pello, Fabian Hofmann, Teele Kuusk, Rana Tahbaz, Thomas Powles, Börje Ljungberg, Axel Bex
Department of Urology, San Raffaele Scientific Institute, Milan, Italy; Division of Experimental Oncology/Unit of Urology, Urological Research Institute, IRCCS San Raffaele Hospital, Milan, Italy. Electronic address: ., Department of Urology, University Hospital Tübingen, Tübingen, Germany; German Cancer Consortium and German Cancer Research Center, Heidelberg, Germany., Department of Cancer Medicine, Gustave Roussy, Université Paris-Saclay, Villejuif, France., Department of Urology, University of Eastern Piedmont, Maggiore della Carità Hospital, Novara, Italy., International Kidney Cancer Coalition, Duivendrecht, The Netherlands., Department of Urology, University Hospital Pilsen, Faculty of Medicine, Charles University, Pilsen, Czech Republic., Department of Urology, Coimbra University Hospital, Coimbra, Portugal., Department of Urology, Charité-Universitätsmedizin Berlin, Berlin, Germany., Department of Urology, Chaim Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel., Department of Translational Medicine, Division of Urological Cancers, Lund University, Kristianstad Central Hospital, Lund, Sweden., Department of Urology, Cabueñes University Hospital, Gijón, Spain., Department of Urology, Sunderby Sjukhus, Umeå University, Luleå, Sweden., Department of Urology, Homerton University Hospital NHS Foundation Trust, London, UK., Department of Urology, Elbe Kliniken, Stade, Germany., The Royal Free NHS Trust and Barts Cancer Institute, Queen Mary University of London, London, UK., Department of Surgical and Perioperative Sciences, Urology and Andrology, Umeå University, Umeå, Sweden., 17The Royal Free London NHS Foundation Trust, London, UK; UCL Division of Surgery and Interventional Science, University College London, London, UK; Department of Urology, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.