Nephrology Service, Walter Reed Army Medical Center, Washington, DC.
Uniformed Services University of Health Sciences, Gainesville, FL; Edward Hebert School of Medicine, Bethesda, MD.
We carried out an analysis of the United States Renal Data System to determine the incidence, risk factors and prognosis of renal cell carcinoma (RCC) in a national population of patients receiving incident long-term dialysis. In Cox regression, male gender, older age, end-stage renal disease caused by obstruction, tuberous sclerosis, focal segmental glomerulosclerosis, as well as acquired renal cysts, were independently associated with RCC. Most cases of RCC in incident long-term dialysis patients occurred in patients without acquired renal cysts. A diagnosis of RCC was associated with increased risk of subsequent mortality overall and in all high-risk groups.
Written by:
Hurst FP, Jindal RM, Fletcher JJ, Dharnidharka V, Gorman G, Lechner B, Nee R, Agodoa LY, Abbott KC. Are you the author?
Reference: Urology. 2011 Apr 2. Epub ahead of print.
doi: 10.1016/j.urology.2011.01.007
PubMed Abstract
PMID: 21459420
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