A total of 20,663 patients with T1A kidney cancer from the SEER database (1988-2006) were analyzed for treatment. Partial nephrectomy, radical nephrectomy and active surveillance were applied in 29%, 66% and 5%, respectively. Partial nephrectomy increased from 6.7% in 1988 to 39.6% in 2006 (p<0.001). In contrast, radical nephrectomy decreased from 86.1% to 54.7% (p<0.001). Active surveillance remained stable with 7.2% compared to 5.7% (p=0.6). On multivariate analysis a more contemporary diagnosis, younger patient age, male gender, Caucasian race, and decreasing tumor size were predictors for partial nephrectomy. Predictors for active surveillance were more historical year of diagnosis, more advanced age, female gender, black race, decreasing tumor size, unmarried marital status, and low socioeconomic status. It was concluded that partial nephrectomy is still under utilized for the treatment of T1A kidney cancer.
Bear in mind that this trial is an urgent call to perform partial nephrectomy for T1a kidney cancer - at least in 80% of cases.
Presented by Maxine Sun, BSc, et al. at the 26th Annual European Association of Urology (EAU) Congress - March 18 - 21, 2011 - Austria Centre Vienna, Vienna, Austria
Reported for UroToday by Christian Doehn, MD, PhD, Department of Urology, University of Lübeck Medical School, Lübeck Germany.
View EAU 2011 Annual Meeting Coverage
