Dept. of Urology, Yamagata University Faculty of Medicine.
Cytokines were the only drugs proven to be effective for advanced renal cell carcinoma(RCC). Introducing the targeted drugs prolonged patients' survival. However, limited high-quality evidence is now available for second-line treatment. Everolimus is effective for patients who have experienced progression of disease after sunitinib and/or sorafenib. Further prospective study including the sequencing of targeted drugs is warranted to develop better treatment strategies.
Article in Japanese.
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Reference: Gan To Kagaku Ryoho. 2011 Jun;38(6):907-10.
PubMed Abstract
PMID: 21677480
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