The role of surgery in advanced renal cell carcinoma: Cytoreductive nephrectomy and metastasectomy - Abstract

Department of Urology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1373, Houston, TX 77030, USA.

 

Renal cell carcinoma (RCC) is considered a relatively rare malignancy worldwide. Around a third of patients with RCC present with metastatic disease, and among those patients treated with nephrectomy with curative intent, more than one-third develop metastases during postoperative follow-up. Due to the absence of curative medical treatments for metastatic RCC, surgery remains the mainstay of therapy. Surgery plays a key role in two aspects: cytoreductive nephrectomy to remove the primary renal tumor in the presence of known metastatic disease, and metastasectomy to remove distant metastatic foci in patients with metastatic RCC.

Written by:
Karam JA, Wood CG.   Are you the author?

Reference: Hematol Oncol Clin North Am. 2011 Aug;25(4):753-64.
doi: 10.1016/j.hoc.2011.05.002

PubMed Abstract
PMID: 21763966

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