Diagnosis and treatment of cystic renal cell carcinoma: A report of 14 cases - Abstract

OBJECTIVE:To explore the diagnosis and treatment of cystic renal cell carcinoma.

METHODS:A total of 14 cases of cystic renal cell carcinoma were reviewed and analyzed. Their age range was 40 to 71 years old. Preoperative CT (computed tomography) scan revealed renal cyst-relative masses in 14 cases. The lesions were accompanied by calcification (n = 4) and with septa (n = 8). The preoperative diagnosis was a complex cystic mass in all but 2. Intraoperative pathological examination was undertaken in 12 cases. The findings were malignant cystic renal clear cell carcinoma (n = 10), renal cyst (n = 1) and multi-cell renal cyst (n = 1). The procedures included radical nephrectomy (n = 6), retroperitoneal laparoscopic radical nephrectomy (n = 4), retroperitoneal laparoscopic partial nephrectomy (n = 2), retroperitoneal laparoscopic cyst unroofed plus radical nephrectomy (n = 1) and retroperitoneal laparoscopic partial nephrectomy plus radical nephrectomy (n = 1).

RESULTS:All 14 cases were confirmed postoperatively as cystic renal clear cell carcinoma. All patients received a mean follow-up period of 26 months (range: 4 - 72). Their overall results were excellent with no evidence of neoplastic recurrence or metastasis.

CONCLUSION: Preoperative CT scan may aid the diagnosis of cystic renal clear cell carcinoma. Intraoperative pathological examination should be performed in suspected cases. Nephron-sparing surgery is indicated. Its prognosis is generally favorable.

Written by:
Liu B, Chen J, Jiang H, Wang S, Shen BH, Jin BY, Xie LP. Are you the author?
Department of Urology, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China.

Reference: Zhonghua Yi Xue Za Zhi. 2011 Nov 1;91(40):2861-2.

PubMed Abstract
PMID: 22333551

Article in Chinese.

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