A patient with a suspected malignancy and pancytopenia warrants much consideration.
Most clinicians would consider bone marrow infiltrative process, heralding a grave prognosis. However, rare occurrence of hemophagocytic lymphohistiocytosis is another diagnostic possibility we should keep in mind. The treatment choices and overall prognosis may differ from patients without hemophagocytosis. We present a case of incidentally found advanced renal cell carcinoma (RCC) concurrent with hemophagocytosis process in the bone marrow. We also discuss the importance of this finding.
Written by:
Chao CT, Kao CC, Lee SY, Ho SJ, Jhuang YJ, Li LH, Kao TW. Are you the author?
Division of Nephrology, Department of Internal Medicine, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.
Reference: Can Urol Assoc J. 2012 Apr;6(2):E64-6.
doi: 10.5489/cuaj.10188
PubMed Abstract
PMID: 22511436
UroToday.com Renal Cancer Section