OBJECTIVE: This study aimed to report the computed tomography (CT) and magnetic resonance imaging (MRI) findings of renal cell carcinoma associated with Xp11.2 translocation in adults.
METHODS: We retrospectively identified 9 adults with renal cell carcinoma associated with Xp11.2 translocation who underwent baseline cross-sectional imaging with CT (n = 9) or MRI (n = 3). All available clinical, imaging, and histopathological records were reviewed.
RESULTS: Mean patient age was 24 years (range, 18-45 years). Eight of 9 cancers demonstrated imaging findings of hemorrhage or necrosis (n = 3), advanced stage disease (n = 2), or both (n = 3) at CT or MRI.
CONCLUSIONS: The possibility of renal cell carcinoma associated with Xp11.2 translocation should be considered for a renal mass seen in a patient 45 years or younger, which demonstrates hemorrhage or necrosis or advanced stage disease at CT or MRI.
Written by:
Dang TT, Ziv E, Weinstein S, Meng MV, Wang Z, Coakley FV. Are you the author?
Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA.
Reference: J Comput Assist Tomogr. 2012 Nov-Dec;36(6):669-74.
doi: 10.1097/RCT.0b013e3182680182
PubMed Abstract
PMID: 23192203
UroToday.com Renal Cancer Section
