Metastatic renal cell carcinoma in the gallbladder is extremely rare, with reported frequencies of less than 0.6% in large autopsy reviews.
Only 40 cases were reported in the literature. We report a first case of gallbladder polypoid tumor revealing metastatic clear cell renal cell carcinoma, which demonstrates the importance of radiological tests, histology and immunohistochemistry when making a definitive diagnosis. These examinations also allow differentiating metastatic clear cell renal cell carcinoma from other polypoid lesions in the gallbladder with clear cell morphology. Cholecystectomy should be performed to obtain a definitive diagnosis and to improve survival in case of solitary metastatic renal cell carcinoma.
Written by:
Ghaouti M, Znati K, Jahid A, Zouaidia F, Bernoussi Z, El Fakir Y, Mahassini N. Are you the author?
Department of Pathology, Ibn Sina Univesity Hospital, Rabat, Morocco.
Reference: Diagn Pathol. 2013 Jan 10;8:4.
doi: 10.1186/1746-1596-8-4
PubMed Abstract
PMID: 23305230
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