Gastropleural and gastropericardial fistulas are abnormal communications between the stomach and the pleural cavity or pericardium.
They are rare and life-threatening complications, which require prompt surgical intervention. We report the case of a gastro-pleuro-pericardial fistula that developed in a patient treated with radiotherapy and then Sunitinib (Sutent(®)), a novel tyrosine-kinase inhibitor, for lung metastases from renal cell carcinoma. To our knowledge, this is the first case of a gastro-pleuro-pericardial fistula developing as a consequence of combined radiation and chemotherapy.
Written by:
Neri A, Lambert Y, Marrelli D, Di Mare G, Mastrogiacomo D, Corso G, Volterrani L, Roviello F. Are you the author?
Section of General Surgery and Surgical Oncology, Department of Human Pathology and Oncology, University of Siena, viale Bracci, Policlinico "Le Scotte", 53100, Siena, Italy.
Reference: Surg Today. 2013 Jan 12. Epub ahead of print.
doi: 10.1007/s00595-012-0475-3
PubMed Abstract
PMID: 23307297
UroToday.com Renal Cancer Section