Preoperative evaluation of perinephric fat invasion in patients with renal cell carcinoma: Correlation with pathologic findings, "Beyond the Abstract," by Sandeep S. Hedgire, MD, et al

BERKELEY, CA (UroToday.com) - Extension of the renal cell carcinoma into adjacent fat can have significant impact on staging and treatment strategies. Cross-sectional imaging can reliably predict perinephric fat invasion during preoperative evaluation of RCC. In our study, CT was more sensitive and MRI was more specific for detection of perinephric fat invasion. Mixed (linear–nodular) pattern was associated with more accurate detection of fat involvement, and the chance of positive pathology report was 2.8 times higher. The negative predictive values (NPVs) of 90% for CT and 86% for MRI emphasize that, in most of the cases, perinephric fat infiltration is unlikely to be present on pathology if it is not detected on CT or MRI preoperatively.


The slides were originally presented at the 2012 Annual Meeting of the American Roentgen Ray Society (ARRS), April 29 - May 4, 2012, Vancouver, BC Canada

Written and prepared by:
Sandeep Hedgire, Azadeh Elmi, Nishad Nadkarni, Kai Cao, Shaunagh Mcdermott, Mukesh Harisinghani as part of Beyond the Abstract on UroToday.com. This initiative offers a method of publishing for the professional urology community. Authors are given an opportunity to expand on the circumstances, limitations etc... of their research by referencing the published abstract.

Division Of Abdominal Imaging and Interventional Radiology
Massachusetts General Hospital- Harvard Medical School
Boston, MA USA

Preoperative evaluation of perinephric fat invasion in patients with renal cell carcinoma: Correlation with pathologic findings - Abstract

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