OBJECTIVE: The objective of this study was to assess the accuracy of multidetector computed tomography (CT) in diagnosing perinephric (PN) and/or renal sinus (RS) fat invasion in patients with renal cell carcinoma (RCC), with reference to the CT findings predictive for the diagnosis of invasion.
METHODS: This was a retrospective study of 48 RCCs. Examinations were performed on a 16-row CT scanner, including unenhanced and 3-phase contrast-enhanced CT scanning. Unenhanced transverse images and multiplanar reformations of each contrast-enhanced CT phase were evaluated. The predictive value of CT findings in diagnosing PN and/or RS fat invasion was determined using multivariate logistic regression analysis.
RESULTS: The CT findings that were most predictive for the diagnosis of PN fat invasion were the presence of contrast-enhancing nodules in the PN fat and tumoral margins. Invasion of the pelvicaliceal system was the most significant predictor in the diagnosis of RS fat invasion.
CONCLUSIONS: Multidetector CT provides satisfactory results in detecting PN and/or RS fat invasion in RCC.
Written by:
Tsili AC, Goussia AC, Baltogiannis D, Astrakas L, Sofikitis N, Malamou-Mitsi V, Argyropoulou MI. Are you the author?
Departments of Clinical Radiology, University Hospital of Ioannina, Ioannina, Greece.
Reference: J Comput Assist Tomogr. 2013 May-Jun;37(3):450-7.
doi: 10.1097/RCT.0b013e318283bc8e
PubMed Abstract
PMID: 23674020
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