Spinal nerve root metastasis of renal cell carcinoma is a rare occurrence.
In addition to treatment of the primary lesion, surgical resection of the nerve root metastasis, occasionally with sacrifice of the involved nerve, is the accepted standard of treatment. Resection often resolves presenting motor and pain symptoms due to relief of neural compression. We describe two patients with nerve root metastasis of renal cell carcinoma and their management. While locally advanced and metastatic renal cell carcinoma has been shown to be chemo- and radio-resistant, immunotherapy is a promising treatment. Given the high prevalence of systemic disease in patients with intradural metastases, systemic (and possibly intracranial) imaging can be used to identify other potential areas of disease.
Written by:
Strong C, Yanamadala V, Khanna A, Walcott BP, Nahed BV, Borges LF, Coumans JV. Are you the author?
Department of Neurosurgery, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Boston, MA 02115, USA.
Reference: J Clin Neurosci. 2013 Aug 6. pii: S0967-5868(13)00150-1.
doi: 10.1016/j.jocn.2013.02.014
PubMed Abstract
PMID: 23931936
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