Tubulocystic renal cell carcinoma (TC-RCC) is a rare renal tumor composed of well-differentiated tubules and cysts lined by neoplastic cells with eosinophilic cytoplasm and prominent nucleoli.
The origin of the tumor cells is still controversial. TC-RCC typically arises unilaterally. Involvement of both kidneys by multifocal TC-RCC has not been reported. In this study we report the first case of bilateral and multifocal TC-RCC. Immunohistochemical, cytogenetic and ultrastructural studies suggest TC-RCC is closely related to papillary RCC.
Written by:
Kong MX, Hale C, Subietas-Mayol A, Lee P, Cassai ND, McRae G, Goldfarb DS, Zhou M, Wieczorek R. Are you the author?
Departments of Pathology, New York Harbor VA Medical Center, New York University School of Medicine, NY; Departments of Medicine, New York Harbor VA Medical Center, New York University School of Medicine, NY; Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH, USA.
Reference: Rare Tumors. 2013 Nov 7;5(4):e57.
doi: 10.4081/rt.2013.e57
PubMed Abstract
PMID: 24416491
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