PURPOSE: More than 50,000 Americans were diagnosed with kidney and renal pelvis cancer in 2010.
The National Program of Cancer Registries (NPCR) and Surveillance Epidemiology and End Results (SEER) combined data include cancer incidence from the entire US. Our work presents updated incidence data, evaluates trends, and adds geographic distribution to the literature.
MATERIALS AND METHODS: We examined invasive, microscopically-confirmed kidney and renal pelvis cancers diagnosed between 2001-2010 and meeting United States Cancer Statistics reporting criteria for each year, excluding cases diagnosed by autopsy or death certificate. Histology codes classified cases as renal cell carcinoma (RCC). Rates and trends were estimated using SEER-Stat.
RESULTS: 342,501 cases of RCC were diagnosed. RCC incidence rates rose from 10.6 per 100,000 in 2001 to 12.4 in 2010 and increased with age until 70-74 years. RCC incidence rates for men were nearly double women. The annual percent change (APC) was higher in women than men. APC was higher for those 20-24 years and for grade III tumors.
CONCLUSIONS: RCC incidence increased from 2001-2010. Asian/Pacific Islanders (API) and those 20-24 years of age had the highest APCs. While some increase results from localized disease, the highest APC was in grade III tumors, indicating more aggressive disease. Continued monitoring of trends and epidemiologic work is warranted to determine risk factors.
Written by:
King SC, Pollack L, Li J, King JB, Master VA. Are you the author?
Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, CDC, 4770 Buford Hwy, Atlanta, GA, 30341; Department of Urology and Winship Cancer Institute, School of Medicine, Emory University, 1365C Clifton Road, Atlanta, Georgia 30322.
Reference: J Urol. 2014 Jan 11. pii: S0022-5347(14)00003-2.
doi: 10.1016/j.juro.2013.12.046
PubMed Abstract
PMID: 24423441
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