Renal cell carcinomas (RCCs) have a tendency to metastasize at an early stage, therefore, the patients frequently exhibit metastatic disease at the time of diagnosis.
Common locations for the metastases are adjacent organs and abdominal lymph nodes; however, occasionally metastasis to the peripheral organs may be the initial clinical symptom. The 71-year-old male patient in the current case suffered from radioresistant and aggressively behaving RCC metastasis in the mandible and lower lip, which was successfully managed by surgical resection. RCC metastasis to the facial area is considered to be uncommon based on a review of the existing literature. RCC are somewhat radioresistant and therefore, palliative surgery must be considered when treating patients with this metastatic disease.
Written by:
Suojanen J, Färkkilä E, Helkamaa T, Loimu V, Törnwall J, Lindqvist C, Hagström J, Mesimäki K. Are you the author?
Department of Oral and Maxillofacial Diseases, Helsinki University Central Hospital, Helsinki FIN-00014, Finland; Department of Oncology, Helsinki University Central Hospital, Helsinki FIN-00014, Finland; The Haartman Institute, Department of Pathology and HUSLAB, Helsinki University Central Hospital, Helsinki FIN-00014, Finland.
Reference: Oncol Lett. 2014 Nov;8(5):2175-2178.
doi: 10.3892/ol.2014.2505
PubMed Abstract
PMID: 25289097