We report 12 renal cell carcinomas in 6 patients with Von Hippel-Lindau (VHL) disease treated with radiofrequency ablation (RFA).
The mean age of the patients was 46 (range 38-53) years (male : 4, female : 2). Computed tomography (CT)-guided transcutaneous RFA was performed under conscious sedation with local anesthetics. The mean size of the tumors was 2.4 (range 0.7-8.1) cm. Nine of the 12 tumors (75%) were locally well controlled. However, 3 tumors in 2 patients developed visceral metastases after RFA. While minimal flank pain, nausea, perinephritic hematoma and lumbago were observed, there was no major complication during or after the procedure. The therapy with CT-guided transcutaneous RFA is efficient and minimal invasive for renal cell carcinoma in patients with VHL, leading to preservation of renal function.
Written by:
Nao T, Shimamoto T, Karashima T, Kamei M, Fukuhara H, Fukata S, Satake H, Ashida S, Yamasaki I, Kamata M, Inoue K, Yamanishi T, Ogawa Y, Ito S, Shuin T. Are you the author?
The Department of Urology, Kochi Medical School; The Department of Urology, Kochi National Hospital; The Department of Diagnostic Radiology and Radiation Oncology, Kochi Medical School; The Department of Diagnostic Radiology, Kochi Red Cross Hospital.
Reference: Hinyokika Kiyo. 2014 Sep;60(9):415-20.
PubMed Abstract
PMID: 25293793
Article in Japanese.