Background. This study aimed to investigate whether diffusion-weighted imaging (DWI) could contribute to the discrimination between benign and malignant renal cancer. Methods. We searched the PubMed electronic database for eligible studies.
STATA 12 0 software was used for statistical analysis The SMD and 95% CI were calculated Results Decreased ADC signal was seen in all renal cancer patients (cancer tissue versus normal tissue: SMD = 1 63 and 95% CI = 0 96~2 29, P < 0 001; cancer tissue versus benign tissue: SMD = 2 22 and 95% CI = 1 53~2 90 and P < 0 001, resp ) MRI machine type-stratified analysis showed that decreased ADC signal was found by all included MRI machine types in cancer tissues compared with benign cancer tissues (all P < 0 05) The ADC values of renal cancer patients were significantly lower than those of normal controls for all included P values (all P < 0 05), and there was a decreased ADC signal at b-500, b-600, b-1000, b-500, and 1000 gradients compared with benign cancer tissues (all P < 0 05) Conclusion Our study concluded that decreased ADC signal presented in DWI may be essential for the differential diagnosis of renal cancer
BioMed research international 2015 Apr 30 [Epub]
Yu Lei, Hong Wang, Hai-Feng Li, Yan-Wei Rao, Jing-Hong Liu, Shi-Feng Tian, Ye Ju, Ye Li, An-Liang Chen, Li-Hua Chen, Ai-Lian Liu, Ming-Li Sun
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