Management of genitourinary (GU) cancers is improving rapidly with the development of immunotherapy agents, especially anti-PD-1/anti-PD-L1 therapies. Large studies have shown better outcomes for the treatment of these patients, leading to new drug approvals and recent changes in standards of care in renal, prostate and bladder cancer. We performed a review of recent studies assessing efficacy of immuno-oncology therapies in GU cancers. New results are summarized and next ways of development of clinical research are discussed as the use of such therapies will soon be assessed in first-line or adjuvant settings.
Bulletin du cancer. 2017 Feb 22 [Epub ahead of print]
Frédéric Bigot, Clément Bonnet, Christophe Massard
University of Paris Sud, Gustave-Roussy Cancer Campus, Drug Development Department and Department of Medical Oncology, 114, rue Édouard-Vaillant, 94805 Villejuif cedex, France., University of Paris Sud, Gustave-Roussy Cancer Campus, Drug Development Department and Department of Medical Oncology, 114, rue Édouard-Vaillant, 94805 Villejuif cedex, France. Electronic address: .