Paraneoplastic syndromes are commonly encountered in renal cell carcinoma, but neurological manifestations are rare. Herein we report a case of a patient with locally advanced renal cell carcinoma who presented with Parkinson-like symptoms which prohibited surgery due to poor performance status. However, a significant improvement was noted after tyrosine kinase inhibitor therapy, allowing the patient to proceed to curative surgery.
Urology case reports. 2017 Jun 19*** epublish ***
Naveed Ali, Alexander Kutikov, Daniel M Geynisman
Department of Hematology/Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA., Department of Surgical Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA.