A whole-transcriptome analysis of gene expression in six samples of clear cell renal cancer was performed. Using bioinformatics methods, we established a relationship between gene expression data and changes in activity of metabolic pathways: in this cancer type, the expression of genes involved in the metabolism of carbohydrates, lipids, and amino acids as well as in energy metabolism changed most significantly.
Doklady. Biochemistry and biophysics. 2017 Jul 20 [Epub]
V Yu Bashmakov, T M Gorbacheva, A V Panevina, S A Solodskikh, I P Moshurov, A A Mikhaylov, A Yu Maslov, V N Popov
Department of Genetics, Cytology, and Bioengineering, Voronezh State University, Voronezh, 394006, Russia. ., Department of Genetics, Cytology, and Bioengineering, Voronezh State University, Voronezh, 394006, Russia., Voronezh Regional Clinical Oncological Dispensary, Voronezh, 394036, Russia.