The most comprehensive sequencing effort of sarcomatoid renal cell carcinoma (sRCC) to date reinforces the notion that the sarcomatoid component is closely related to the epithelial component of the cancer. This work also challenges the notion that sRCC evolves from low grade RCC and identifies potential mediators of sarcomatoid differentiation.
Clinical cancer research : an official journal of the American Association for Cancer Research. 2017 Sep 14 [Epub ahead of print]
Paulo Bergerot, Neeraj Agarwal, Sumanta Kumar Pal, Jeremy O Jones
Medical Oncology & Experimental Therapeutics, City of Hope Comprehensive Cancer Center., Medicine, Huntsman Cancer Institute., Cancer Biology, City of Hope Comprehensive Cancer Center .