Robot-assisted imaging-guided sentinel lymph node biopsy is a novel technique that has not been widely investigated in testicular germ cell tumor (GCT). Current staging strategies have poor accuracy for prediction of occult metastatic disease in clinical stage I GCT. Feasibility studies have used 99mTc-nanocolloid staining during laparoscopic procedures. The RAISN trial is investigating robot-assisted lymph node resection guided by indocyanine green fluorescence imaging. This new diagnostic approach is potentially more precise and easier to apply, and is widely available. Confirmation of its utility could change the management of newly diagnosed GCT by reducing overtreatment and treatment-related toxicity.
European urology open science. 2024 Jun 27*** epublish ***
Marieke Sofie Vermeulen-Spohn, Pailin Pongratanakul, Sophia Thy, Juergen Dukart, Peter Albers, Yue Che
Department of Urology, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Institute of Neurosciences and Medicine, Forschungszentrum Jülich, Jülich, Germany.