PURPOSE OF REVIEW: This overview discusses several important developments in testicular germ cell tumors (TGCTs) over the past year.
RECENT FINDINGS: Genomic studies continue to investigate gene expression as possible markers for disease relapse and metastatic potential. Optimal treatment strategies for early-stage seminomas continue to evolve toward surveillance versus chemotherapy, although developing radiation delivery modalities may ultimately provide a safe alternative. The role of retroperitoneal lymph node dissection in postorchiectomy early-stage nonseminoma germ cell tumors remains a topic of debate.
SUMMARY: Treatment paradigms continue to be refined for TGCTs as research in these areas continues.
Written by:
Nallu A, Chimakurthi R, Hussain A, Mannuel HD. Are you the author?
Department of Medicine, University of Maryland School of Medicine; Baltimore Veterans Affairs Medical Center; Department of Medicine, Pathology and Biochemistry, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Reference: Curr Opin Oncol. 2014 May;26(3):294-8.
doi: 10.1097/CCO.0000000000000068
PubMed Abstract
PMID: 24675234
UroToday.com Testicular Cancer Section
