AUA 2023 VL

Deep PSA Response Following Addition of Darolutamide to ADT and Docetaxel in ARASENS - Fred Saad

Details
Zach Klaassen hosts a discussion with Fred Saad about the ARASENS data and its transformative impact on prostate cancer treatment. This conversation primarily explores the correlation between a rapid, deep, and durable PSA response and excellent patient outcomes. Dr. Saad underlines the biological significance of a decline in PSA, noting how patients who achieve undetectable PSA levels significant...

Transgender Women and Prostate Cancer: Revealing an Underestimated Disease Burden - Stephen J. Freedland

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In a conversation between Alicia Morgans and Stephen Freedland, they discuss a study exploring prostate cancer in transgender women. Previously, such cases were thought to be exceedingly rare, based on limited case reports. However, Dr. Freedland's team delved deeper, reviewing entire Veterans Affairs’ records to identify 155 transgender women diagnosed with prostate cancer. The number indicates t...

DEAR: Comparative Real-World Evidence on Darolutamide, Enzalutamide, and Apalutamide for Patients with nmCRPC in the United States - Neal D. Shore

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Alicia Morgans engages with Neal Shore about the DEAR study, an analysis of real-world outcomes for non-metastatic castration-resistant prostate cancer (nmCRPC) patients treated with darolutamide, apalutamide, and enzalutamide. The study is made possible by an organization called PPS, which has access to electronic data. It includes information about when patients started their treatments, associa...

Immersive Virtual Reality (iVR) for Percutaneous Nephrolithotomy: The More You Know, the Better the Outcome Presentation - Andrei D. Cumpanas

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The study presented by Andrei Cumpanas examined the benefits of using an immersive virtual reality model before percutaneous stone removal in 125 patients. The study found that the use of immersive virtual reality resulted in an improved understanding of intra-renal anatomy, better surgical outcomes, and a reduced rate of complications. The group that viewed the virtual reality model had higher ra...

Exploring Leadership, Mentorship, and Sponsorship in Urology - Kirsten L. Greene

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In this discussion Zach Klaassen speaks with Kirsten Greene about her interpretation of leadership and its importance. Dr. Greene shares that leaders may inspire, innovate, or challenge problematic issues, characteristics that her past mentors embodied. She identifies mentors not only as senior figures but also as peers or juniors who can inspire others to challenge themselves. Throughout her care...

The Application of Artificial Intelligence for Renal Stone Volume Determination: Ready for Prime Time? - Andrei D. Cumpanas

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In a research presentation from Andrei Cumpanas, significant strides are shown in using artificial intelligence to accurately determine renal stone volume. Traditional linear measurements prove inaccurate due to stones' irregular shapes, leading the team to train an AI neural network for kidney segmentation and CT-based stone volume calculation. Cumpanas reports an impressive advancement in the ac...

Fluid Temperature Effect on Superpulse Thulium Fiber Laser Stone Ablation - Andrei D. Cumpanas

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Andrei Cumpanas presents a study on the impact of fluid temperature on stone ablation using superpulse thulium fiber laser. The study finds that warming the irrigation fluid to 37 degrees Celsius significantly increases the laser's efficiency in ablating urinary stones, enhancing the process by 12 to 29%. The effect is most notable on uric acid and calcium oxalate dihydrate stones. This research p...

Exploring Regional Variation in Genomic Testing and Imaging in Prostate Cancer - Michael S. Leapman

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In an interview with Matthew Cooperberg, Michael Leapman discusses his research on the use of genomic tests and imaging in prostate cancer and the resulting national practice patterns. Leapman found significant regional variation in the utilization of these tests, with areas rich in urologists and prostate cancer care showing higher adoption rates. He also observed a correlation between increased...

Exploring Unique Aspects of Prostate Cancer Research in the VA Healthcare System: Diversity, Disparities, and Future Directions - Isla P. Garraway

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In this conversation, Isla Garraway discusses the unique aspects of prostate cancer research within the VA healthcare system with Matthew Cooperberg. They highlight the diversity of the veteran population served by the VA, including racial, ethnic, and geographic diversity, and the importance of understanding how prostate cancer impacts different groups. The discussion covers disparities in prosta...

Trends in Prostate Cancer Diagnosis in Transgender Women - Farnoosh Nik-Ahd

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In this conversation, Alicia Morgans and Farnoosh Nik-Ahd discuss the diagnosis of prostate cancer in transgender women. Dr. Nik-Ahd highlights that despite gender affirmation surgeries, transgender women, who were assigned male at birth, retain their prostates and therefore remain at risk for prostate cancer. Using data collected from the Veterans Health Administration, she discusses the complexi...