Assessing Alterations in Stone Burden Among Patients with Medullary Sponge Kidney: A Volumetric Approach “Presentation”
May 4, 2024
Andrei Cumpanas presented a study on assessing alterations in stone burden among patients with Medullary Sponge Kidney (MSK), showing that CT reports often miss increases in stone volume in MSK patients, leading to a false sense of stable disease.
Biography:
Andrei D. Cumpanas, MD, Researcher, Department of Urology, The University of California, Irvine, CA
Biography:
Andrei D. Cumpanas, MD, Researcher, Department of Urology, The University of California, Irvine, CA
Read the Full Video Transcript
Andrei D. Cumpanas: Dear viewers, my name is Andrei Cumpanas. I'm a LIFT Research Scholar here at University of California Irvine's Department of Urology, and today I'll be presenting the results of our study, Assessing Alterations in Stone Burden Among Patients with Medullary Sponge Kidney: A Volumetric Approach. We sought to assess the accuracy of the year-to-year computerized tomography reports of stable stone burden among MSK patients versus urolithiasis patients without an underlying renal disorder. 70 patients, 20 MSK, 50 non-MSK, with a stable CT report were retrospectively included in this study. Using the 3D Slicer software, CT-based volumetric stone burdens were determined. Among the MSK and non-MSK patients with a stable report, we assessed the rate in failing to detect increases in stone volume.
In the MSK group, stone burden increases of 15%, 25 percent, and 50% were missed in 49, 39, and 20% of patients respectively. Moreover, an MSK diagnosis was associated with an incorrect assessment of unchanged stone burden for all growth thresholds, with p-values of less than 0.03. In conclusion, the increase in MSK stone burden on CT reports is often missed, leading to a false sense of stable disease.
Thank you.
Andrei D. Cumpanas: Dear viewers, my name is Andrei Cumpanas. I'm a LIFT Research Scholar here at University of California Irvine's Department of Urology, and today I'll be presenting the results of our study, Assessing Alterations in Stone Burden Among Patients with Medullary Sponge Kidney: A Volumetric Approach. We sought to assess the accuracy of the year-to-year computerized tomography reports of stable stone burden among MSK patients versus urolithiasis patients without an underlying renal disorder. 70 patients, 20 MSK, 50 non-MSK, with a stable CT report were retrospectively included in this study. Using the 3D Slicer software, CT-based volumetric stone burdens were determined. Among the MSK and non-MSK patients with a stable report, we assessed the rate in failing to detect increases in stone volume.
In the MSK group, stone burden increases of 15%, 25 percent, and 50% were missed in 49, 39, and 20% of patients respectively. Moreover, an MSK diagnosis was associated with an incorrect assessment of unchanged stone burden for all growth thresholds, with p-values of less than 0.03. In conclusion, the increase in MSK stone burden on CT reports is often missed, leading to a false sense of stable disease.
Thank you.