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- Shilpa Gupta and Petros Grivas engage in a discussion about lessons learned from immunotherapy use across different cancer types and their application to urothelial cancer. The conversation explores contrasting approaches between kidney cancer, where immunotherapy rechallenge after progression shows no benefit, and melanoma, where immunotherapy rechallenge remains acceptable. They examine the chal...
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- Ashish Kamat speaks with Sunil Patel about a BCAN Think Tank breakout session focused on occupational and environmental risk factors in bladder cancer prevention. The discussion explores the impact of exposure to burn pits among military veterans and environmental hazards faced by firefighters, highlighting the complex mixture of potential carcinogens including polycyclic aromatic hydrocarbons, he...
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- Ashish Kamat speaks with Janet Kukreja about a working group session at the BCAN Think Tank, focusing on establishing excellence in community-based bladder cancer care. The discussion explores findings from a collaboration between BCAN and the Association of Cancer Care Centers, highlighting challenges faced by community practices in delivering comprehensive bladder cancer treatment. Key issues in...
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- Leslie Ballas speaks with Kimberley about quality of life considerations for bladder cancer patients undergoing trimodality therapy (TMT), following discussions at the Bladder Cancer Advocacy Network Think Tank. The conversation explores various aspects of patient outcomes, including sexual health differences between men and women, the rarity of salvage cystectomy, and challenges in collecting qua...
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- Zachary Klaassen speaks with Sarah Psutka about cognitive resilience in bladder cancer care. Dr. Psutka explains how cancer treatment, from surgery to chemotherapy, can significantly impact cognitive function, with up to a third of patients experiencing persistent postoperative cognitive dysfunction. She emphasizes the shift from focusing solely on physical frailty to understanding patients' compl...
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- Ashish Kamat talks with Andrea Apolo about implementing new treatment standards in bladder cancer, focusing on the recent EV-302 and CheckMate-901 trials. Dr. Apolo explains how enfortumab vedotin plus pembrolizumab has emerged as the new standard of care for metastatic urothelial carcinoma, showing superior survival outcomes compared to traditional platinum-based chemotherapy. They explore the ch...
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- Laura Bukavina joins Ashish Kamat to discuss the cancer microbiome and nutrition session at the BCAN Think Tank. Dr. Bukavina discusses key presentations on fecal microbiota transplants (FMT) in cancer treatment, highlighting promising results in lung cancer and melanoma. She emphasizes the potential of FMT to improve treatment responses and reduce toxicity. The conversation covers NCI funding opp...
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- David McConkey discusses the application of artificial intelligence (AI) in bladder cancer research, focusing on AI pathology. He outlines ongoing collaborations between cooperative groups and industry partners to develop and validate AI tools for cancer diagnosis and treatment prediction. Dr. McConkey emphasizes the importance of open access data, quality control, and rigorous validation in AI re...
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- Roger Li discusses findings from a patient panel at the BCAN Think Tank, focusing on decision-making in BCG-unresponsive and muscle-invasive bladder cancer treatment. He emphasizes the emotional journey patients undergo and the importance of empowering them with information. Dr. Li highlights several patient stories, demonstrating diverse treatment choices ranging from bladder-sparing approaches t...
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