Genomic Classifier in Prostate Cancer: Active Surveillance VL

2024 NCCN Guidelines: Simplifying the Management of Very Low-Risk Prostate Cancer - Rashid Sayyid & Zachary Klaassen

Details
Rashid Sayyid and Zach Klaassen review the 2024 NCCN Guidelines for managing very low-risk prostate cancer. Dr. Sayyid defines very low-risk prostate cancer using criteria like T1C stage, PSA levels, and biopsy characteristics. The updated guidelines simplify management based on life expectancy: patients with 10 years or more are recommended active surveillance, while those with less are advised o...

Active Surveillance: Optimizing the Quality of Life in Men with Localized Prostate Cancer - Preston Sprenkle & Randy Vince

Details
Preston Sprenkle and Randy Vince join Ashley Ross to discuss active surveillance and the benefits of risk stratification for localized prostate cancer. They collectively emphasize the importance of monitoring cancer closely and intervening with curative intent if it becomes aggressive while minimizing morbidity and improving quality of life. Dr. Vince highlights the Michigan Urological Surgery Imp...

The Molecular Biology of Prostate Cancer - Christopher Barbieri

Details
Christopher Barbieri joins Matthew Cooperberg for a discussion about the molecular biology of localized prostate cancer. Dr. Barbieri explains how the underlying molecular and genomic features that separate prostate cancer subtypes can be studied using DNA sequencing and RNA sequencing. The conversation covers predictive markers including DECIPHER, PAM50, genomic mutations, and oncogenic drivers....