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- Rashid Sayyid and Zach Klaassen scrutinize a publication from European Urology comparing the diagnostic accuracy of PSMA PET and traditional imaging modalities in initial staging of intermediate to high-risk prostate cancer. The authors systematically review studies comparing PSMA-PET/CT, MRI, and conventional imaging, noting that PSMA-PET/CT shows higher sensitivity and specificity. They also dis...
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- Philip Koo discusses the newly updated PSMA PET/CT: Joint EANM, SNMMI procedure guideline, version 2.0, with its first and senior authors, Wolfgang Fendler and Ken Herrmann from Germany. The updated guideline, considered a landmark paper, integrates new ligands and types of imaging, consolidating information on PSMA imaging for different ligands and formalizing them as a class of ligands. It featu...
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- Phillip Koo welcomes Ken Herrmann to discuss Herrmann’s team's latest article, "Tackling the Last Mile: A Major Component to Successfully Established Radioligand Therapy," arguing the importance of 'the last mile' of treatment delivery in nuclear medicine. Drawing parallels with the logistics industry, Herrmann emphasizes the need for flawless delivery of therapy to patients, with patient awarenes...
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- David Crawford joins Phillip Koo in a discussion on the Radiographic Assessments for Detection of Advanced Recurrence (RADAR) articles, which aimed to improve the appropriate utilization of imaging in prostate cancer patients. The RADAR articles looked at three areas: biochemical failure, newly diagnosed disease, and castrate-resistant non-metastatic disease. They suggested appropriate triggers fo...
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- Philip Koo interviews Michael Kipper about the peer-to-peer PYLARIFY reader assistance program. Aimed at educating healthcare providers in accurately reading and interpreting PYLARIFY scans, the program seeks to enhance patient care and harmonize reporting across institutions. Dr. Kipper emphasizes that this initiative is not meant for over-reading studies but to extend understanding of PYLARIFY r...
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- In a recent led by Phillip Koo, Andrei Gafita and Wolfgang Fendler provide valuable insights on their innovative research, demonstrating the potential of PSMA PET imaging as a response to therapy tool in prostate cancer. Their study highlights the inconsistencies between PSMA PET responders and PSA levels, with about 50% of patients exhibiting this discrepancy. They found that PSMA PET imaging may...
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- Matthew Cooperberg is joined by Tom Hope and Jeremie Calais in a discussion PSMA PET agents that have been approved by the US Food and Drug Administration (FDA) and their effect on clinical practice. Positron Emission Tomography (PET) nuclear imaging technique is used to detect prostate cancer. Combining PET with Prostate Specific Membrane Antigen (PSMA) helps doctors to specifically identify pros...
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- Ashley Ross and Alicia Morgans discuss the use of PSMA PET scans in the metastatic CRPC and how the recommendations and guidance have evolved in the NCCN guidelines. Dr. Ross gives an overview of the relevant clinical trials and FDA approvals of key radiotracers and their impact on clinical practice and treatment sequencing, as well as the impact of supply line problems on implementation. Biograph...
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- Phillip Koo speaks with Masoom Haider about the potential of radiomics and machine learning in prostate cancer diagnosis and treatment. Dr. Haider explains that radiomics quantifies information in medical images, such as MRIs, to extract valuable data that can be analyzed using machine learning techniques. This could lead to better risk profiles for patients and more precise treatment plans. Howev...
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- Peter Choyke, a presenter at the 2022 AdMeTech Global Summit for Prostate Cancer, joins Phillip Koo to discuss prostate MRI and the upcoming 6th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer. In November 1997, AdMeTech Foundation was established as a Nonprofit Corporation for the Advancement of Medical Technologies, with a priority focus on the advancement of prostate cance...
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