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- Bernard Bochner joins Ashish Kamat in this discussion discussing the advancements throughout 2020 in muscle-invasive non-metastatic bladder cancer. It would be impossible to discuss the year without mentioning the impact of COVID-19. There are some diseases that can withstand treatment delay, but muscle-invasive bladder cancer is not one of those tumors. These challenges pushed the bladder cancer...
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- Management decisions at presentation are critical for survival— a talk by Curtis A Pettaway, MD. Although primary urethral carcinoma (UC) is rare, with an incidence of 4.3 per million in men and 1.5 per million in women, recurrence is associated with distant metastases. Therefore, physicians will want to be alert to the possibility of UC when, for example, the patient has a urethral protrusion. Th...
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- The Phase 3 data from the United States clinical trial evaluating an investigational gene therapy, nadofaragene firadenovec (rAd-IFN/Syn3), for the treatment of patients with high-grade, Bacillus Calmette-Guérin (BCG) unresponsive non-muscle invasive bladder cancer (NMIBC) was recently published in The Lancet Oncology. In this conversation with Dr. Ashish Kamat, Girish Kulkarni, MD discusses the k...
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- In this conversation with Ashish Kamat, MD, Arjun Balar, MD, MBBS, discusses testing the concept of effectively treating bladder cancer without needing chemotherapy in the non-muscle-invasive disease space, specifically patients with high-risk carcinoma in situ, with or without papillary tumors that had become unresponsive to Bacillus Calmette-Guerin (BCG) based on the current Federal Drug Adminis...
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- Ashish Kamat welcomes Karen Sachse, a patient advocate for the Bladder Cancer Advocacy Network (BCAN) who shares her perspective on non muscle-invasive bladder cancer, the various trials that are ongoing, and the future of various studies. As a bladder cancer survivor diagnosed in 2010 at age 54 with high grade non-muscle invasive bladder cancer, she is disease-free since 2014. Biographies: Karen...
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- Co-chair of the Bacillus Calmette Guerin (BCG)-unresponsive non-muscle-invasive bladder cancer session during the 2020 Virtual Bladder Cancer Advocacy Network Think Tank (BCANTT) meeting, Peter Black, MD joins Ashish Kamat, MD, MBBS providing a succinct overview of this session highlighting the clinical and the translational panel which addresses defining treatment failure after BCG treatment for...
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- Param Mariappan, MBBS, FRCS(Urol), PhD, and Prashant Patel, MBBS, MS, FRCSEd, FRCSEd (Urol), PhD, join Ashish Kamat, MD, MBBS, and discuss transurethral resection of bladder tumor (TURBT). Dr. Mariappan begins by explaining the importance of quality indicators for TURBT. He emphasizes the importance of having a comprehensive checklist of quality indicators. Dr. Patel discusses the current challeng...
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- Eva Comperat and Hikmat Al-Ahmadie, MD, join Ashish Kamat, MD, MBBS to challenge the use of immunohistochemistry, or traditional pathology, versus molecular subtyping in bladder cancer. Dr. Comperat discusses immunohistochemistry, explaining it is more precise, and because it is standardized and more widely used than molecular subtyping, it remains the gold standard. Dr. Al-Ahmadie continues by de...
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- Ashish Kamat, MD, welcomes Makarand Khochikar, President of the Urological Society of India – West zone and Chairman of the Department of Uro-oncology at Siddhi Vinayak Ganapati Cancer Hospital in Miraj joins to discuss a bladder cancer case from Dr. Khockikar’s case files. In this particular case, Dr. Khockikar reviews the cystoscopy of a 65-year-old male presented with intermittent hematuria and...
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- In a conversation with Ashish Kamat, MD, MBBS, Makarand Khochikar, MS DNB, Dip Urol, FRCS, FEBU, presents a bladder cancer case study focusing on a patient with invasive T2 N0 M0 high-grade urothelial carcinoma. Dr. Khochikar describes both the process of perioperative counseling with the patient and the radical cystectomy that was surgically performed. Dr. Khochikar walks through the procedure an...
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