The prevalence of kidney stones is rising and historically carries a preponderance for males. However, recent evidence has questioned whether this gender gap is closing. The aim of this systematic review was to examine this further as well as evaluate possible underlying causes.
Recent evidence confirms the disparity in kidney stone disease between genders is closing. In the modern era, the rise in prevalence among females has been greater, especially in adolescence. Quality of life is also more adversely affected by kidney stone events among females who are also more likely to develop sepsis after endourological surgery. Males, however, are more likely to present with stone events during periods of high ambient temperatures Recent literature demonstrates a temporal change in the disease burden of KSD among men and women. The latter, especially adolescent females, are more likely to develop KSD in their lifetime compared to previous eras. Determining causation is complex and continued research is warranted.
Current urology reports. 2021 Oct 08*** epublish ***
Kathryn Gillams, Patrick Juliebø-Jones, Siri Øvereng Juliebø, Bhaskar K Somani
Department of Urology, Great Western Hospital Swindon, Swindon, UK., Department of Urology, Haukeland University Hospital, Bergen, Norway. ., Department of Gynaecology, Telemark County Hospital, Skien, Norway., Department of Urology, University Hospital Southampton, Southampton, UK.
PubMed http://www.ncbi.nlm.nih.gov/pubmed/34622358