Squamous cell carcinoma on top of urethral stricture: Case report and review of the literature - Abstract

INTRODUCTION: Urethral stricture is a common urological condition, resulting from trauma or venereal infections.

The aim of our study was to report a rare case of squamous cell carcinoma of the penis and pseudoepitheliomatous hyperplasia (PEH) of scrotal skin, on top of repeatedly managed urethral stricture which was of unknown aetiology.

METHODS: A Medline search of publications studying the association of urethral stricture with penile cancer was done.

RESULTS: Two case reports were identified that described two occurrences, which were separated by a few months.

CONCLUSION: Repeated management of urethral stricture with visual urethrotomy or urethral dilation may result in a chronic inflammatory status, predisposing to PEH and squamous cell carcinoma of the genital organs.

Written by:
Kotb AF, Attia D, Ismail AM, Elabbady A.   Are you the author?
Urology department, Faculty of Medicine, Alexandria University, Al Khartom Square, Azarita, Alexandria, Egypt.

Reference: Ecancermedicalscience. 2013 Apr 11;7:304.
doi: 10.3332/ecancer.2013.304


PubMed Abstract
PMID: 23589733

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