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- Stephen Freedland presents the manuscript entitled A Phase 3 Randomized Study of Enzalutamide Plus Leuprolide and Enzalutamide Monotherapy in High-Risk Nonmetastatic Hormone-Sensitive Prostate Cancer with Rising PSA After Local Therapy: EMBARK Study Design. The objective of EMBARK was to value the efficacy and safety of enzalutamide in combination with leuprolide acetate or monotherapy compared wi...
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- Alicia Morgans interviews Fred Saad about a new analysis within the HERO data, focusing on the impact of Body Mass Index (BMI) on the efficacy of Relugolix, an oral antagonist used in androgen deprivation therapy for prostate cancer. Dr. Saad reveals that the study compared Relugolix with Leuprolide across patients with varying BMIs. The findings are reassuring: irrespective of BMI, Relugolix's ef...
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- Philip Koo and Alicia Morgans discuss the evolving role of nuclear medicine in the multidisciplinary care of patients receiving radium-223 for metastatic CRPC (Castration-Resistant Prostate Cancer). Dr. Koo advocates for the emergence of "nuclear oncology" as the fourth pillar in comprehensive cancer programs, emphasizing the need for enhanced communication and collaboration among medical oncologi...
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- Alicia Morgans and Brittany Szymaniak address the intricacies of germline genetic testing in prostate cancer. They delve into the current NCCN and AUA guidelines, noting challenges in aligning these with practical implementation. Both experts highlight the lag in prostate cancer genetic testing compared to other cancers like breast and ovarian. They explore alternative models for pre-test and post...
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- Alicia Morgans and Brenda Martone delve into the critical role of germline and somatic genetic testing in managing metastatic prostate cancer. Dr. Martone emphasizes the NCCN guidelines, which recommend offering both types of testing to patients with high-risk or metastatic disease. The conversation highlights the importance of family history and the broader implications of germline mutations, not...
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- Brenda Martone and Alicia Morgans delve into the nuanced use of Radium for treating patients with metastatic CRPC (Castration-Resistant Prostate Cancer). Dr. Martone emphasizes that Radium is not just for alleviating bone pain but can also address other symptoms like fatigue and loss of appetite. She notes that the drug can be used at any point in the treatment continuum, depending on patient need...
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- Drs Maha Hussain and Fred Saad join Dr Alicia Morgans in a conversation on PARP combination therapy in prostate cancer and the status of its use in clinical practice. In this context, the group discusses the PROpel and the MAGNITUDE studies data and how the data can be used in clinical practice. Biographies: Maha Hussain, MD, FACP, FASCO, is the Genevieve Teuton Professor of Medicine in the Divisi...
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- Oliver Sartor is joined by Alicia Morgans to discuss her presentation at the GU ASCO 2022 Annual Meeting on the largest digital survey conducted in patients with prostate cancer, the initial results of an international survey of patients with prostate cancer. The goal of this survey was to map patient experiences, expectations, and attitudes, and to identify challenges and unmet needs in diagnosis...
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- Andrey Soares joins Phillip Koo at the 13th International Uro-Oncology Conference in Sao Paulo, Brazil in a conversation on challenges and opportunities in the management of patients with high risk localized disease in Latin America as well as the ARASENS data in the metastatic castration sensitive prostate cancer setting. Dr, Soares elaborates on the work that still needs to be done in Brazil to...
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- Nicholas James joins Phillip Koo at the 13th International Uro-Oncology Conference in Brazil to discuss his presentation on the lessons learned from the STAMPEDE trial which shed insight into how we can improve the outcomes for men with metastatic prostate cancer. Professor James' lecture focuses on how Latin American countries can implement these lessons in conducting and setting up clinical tria...
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